(Provera) Medroxyprogesterone acetate, administered orally or parenterally in the recommended doses to women with adequate endogenous oestrogen, transforms proliferative into secretory endometrium. Androgenic and anabolic effects have been noted, but medroxyprogesterone acetate is apparently devoid of significant oestrogenic activity.
Why is Provera prescribed?
Provera is derived from the female hormone progesterone. You may be given Provera if your menstrual periods have stopped or a female hormone imbalance is causing your uterus to bleed abnormally. Provera is also prescribed to prevent abnormal growth of the uterine lining in women taking estrogen replacement therapy. Other forms of Provera, such as Depo-Provera, are used as a contraceptive injection and prescribed in the treatment of endometrial cancer.
Some doctors prescribe Provera to treat endometriosis, menopausal symptoms, premenstrual tension, sexual aggressive behavior in men, and sleep apnea (temporary failure to breath while sleeping).
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Most important fact about Provera
You should never take Provera during the first 4 months of pregnancy. During this formative period, even a few days of treatment with Provera might put your unborn baby at increased risk for birth defects. If you take Provera and later discover that you were pregnant when you took it, discuss this with your doctor right away.
How should you take Provera?
Provera may be taken with or between meals. Do not change from one brand to another without consulting your doctor or pharmacist. --If you miss a dose...Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. Never take 2 doses at the same time. --Storage instructions...
Store at room temperature.
What Provera side effects may occur?
Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Provera.
Side effects may include:
Acne, anaphylaxis (life-threatening allergic reaction), blood
clot in a vein, lungs, or brain, breakthrough bleeding (between
menstrual periods), breast tenderness or sudden or excessive
flow of milk, cervical erosion or changes in secretions, depression,
excessive growth of hair, fever, fluid retention, hair loss,
headache, hives, insomnia, itching, lack of menstruation,
menstrual flow changes, spotting, nausea, rash, skin discoloration,
sleepiness, weight gain or loss, yellowed eyes and skin
Recommended Provera dosage
ADULTS To Restore Menstrual Periods
Provera Tablets are taken in dosages of 5 to 10 milligrams daily for 5 to 10 days. Make sure you discuss what effect this will have on your menstrual cycle with your doctor. You should have bleeding 3 to 7 days after you stop taking Provera. Abnormal Uterine Bleeding Due to Hormonal Imbalance Beginning on the 16th or 21st day of your menstrual cycle, you will take 5 to 10 milligrams daily for 5 to 10 days. Make sure you discuss what effect this will have on your menstrual cycle with your doctor. You should have bleeding 3 to 7 days after you stop taking Provera. To Accompany Estrogen Replacement Therapy
The recommended regimen is 5 or 10 milligrams of Provera a day for 12 to 14 days each month, beginning on either Day 1 or Day 16 of the cycle.
Provera Overdosage
Although no specific information is available, any medication taken in excess can have serious consequences. If you suspect an overdose of Provera, seek medical attention immediately.
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