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Ingredient
Lufenuron + milbemycin
Generic Name
Milbemycin Oxime (mil’-beh-my’-sin ox’-eem) and Lufenuron (lew-fen’-your-on)
Brand Name(s)
Sentinel (Novartis)
What is Sentinel used for
Sentinel with Lufenuron is used in the prevention of heartworm disease and in the control of hookworm, roundworm and whipworm. When combined with Lufenuron it is also used to control fleas by preventing the development of flea eggs. The medication does not kill adult fleas.
Sentinel Availability
Sentinel with Lufenuron is available by prescription as chewable Flavor Tabs.
How Sentinel should be used
Sentinel with Lufenuron is indicated for use in dogs and puppies four weeks of age and older, and two pounds body weight or greater. The usual dose of Sentinel with Lufenuron for dogs 2-10 pounds is 2.3mg/46mg, 11-25 pounds is 5.75mg/115mg, 26-50 pounds is 11.5mg/230mg and 51-100 pounds is 23mg/460mg given once a month year round. An alternate treatment is to give this medication once a month during the mosquito season and also one month after the season ends.
What are the Sentinel side effects
Side effects of Sentinel with Lufenuron are rare although some animals may exhibit depression, drowsiness, vomiting, itching, hives, loss of appetite, diarrhea, seizures, convulsions, hypersalivation and weakness.
What special Sentinel precautions are there
Sentinel should not be used in animals allergic to it. The pet should be tested for heartworm disease before starting this medication. If the pet has been off heartworm preventative for 6 months or more, retest in 6 months since microfilaria, that take 6 months to mature, will cause a positive test result. Because humans can contract hookworm and roundworm from animals it is important to maintain good personal hygiene. It is also important to eliminate fleas on the pet and in the household and to not feed the pet rodents or uncooked meat or fish. To prevent reinfection, daily cleanup of stools is recommended.
In the event of Sentinel overdose
Contact your veterinarian or veterinary emergency room.
How should I store Sentinel
Keep Sentinel in the original box. Do not remove the Sentinel tablet from the foil wrap until ready to give the medication. Keep Sentinel out of the reach of children and pets.
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