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Bupropion information for people that are required to take this medicine
Bupropion are classified as an antidepressant drug. It works by inhibiting the reuptake of dopamine, norepinephrine and serotonin—these are chemical substances called neurotransmitters that are found in the body, which allows the electrical impulses be delivered from neuron to neuron. Bupropion is prescribed to people with SAD or seasonal affective disorder, which may be described as presenting episodes of depression at a certain time of year (usually during winter), and to people with major depressive disorder.
Dosage and Administration:
This medication is available in tablets: 75, 100, and 150 mg. It is also available in sustained-release tablets: 100, 150, and 200 mg. In extended release tablets; available dosages per tablet are 150 and 300 mg.
Bupropion is usually given in one, two or three daily doses. If it is prescribed for depression, the recommended dose of is 100 mg 3 times daily (300 mg/day) for immediate-release tablet; the maximum dose is 450 mg daily. Initially, the dose is 100 mg two times a day. The doctor may increase the dosage to 100 mg 3 times daily after three days.
For sustained-release tablets, it is given 150 mg daily. Extended-release tablets is initially given 150 mg daily; with a target dose of 300 mg daily and a maximum dose is 450 mg daily.
If it is indicated to stop smoking, it is usually given initially at 150 mg once daily for three days. If you can tolerate the starting dose, the dose is changed (increased). Two weeks after starting Bupropion therapy, smoking is discontinued.
Drug Interactions:
• Carbamazepine (Tegretol) may affect Bupropion’s effects on the body, reducing its potency. The blood concentration of this drug may be reduced.
• Bupropion should never be used together with MAOIs or monoamine oxidase inhibitors or within at least 14 days of stopping from taking it with one of them.
• It may also affect the action of warfarin (Coumadin).
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