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Reasons Didronel is used and important information about this medication
Contents of Didronel tablet is etidronate disodium 200mg or 400mg, magnesium stearate, microcrystalline cellulose, and starch. Etidronate disodium is responsible for inhibiting normal and abnormal bone resorption and reduces bone formation. Absorption of the drug reach to approximately 3%, while 50% of it is distributed within the bones, and this does not cross through blood-brain barrier. It is not metabolized, and for unabsorbed drugs, it is excreted through feces, while some of it is released in the urine in 24 hours, and the remaining contents are distributed and absorbed in bone compartments and it is slowly eliminated by the body.
Didronel acts primarily in the bones, studies showed that the approximate residence time of the drug in the bone may vary due to some factors such as metabolic conditions and bone type of a person. This drug is also used to decrease high calcium level in the blood, especially for cancer patients.
Stomach upsets such diarrhea and nausea may occur while taking the drug. Some of the complaints are alleviated by dividing its total daily dose. Other serious side effects include worsening bone or joint pain, muscle pain, jaw pain, mood changes, and signs of infection. But allergic reactions are rare, and it’s good to seek medical attention to any OCCURING symptoms.
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