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Reasons Mirapex is used and important information about this medication
The drug named Mirapex is classified as an antiparkinsonian. It is a dopamine D1 and dopamine D2 receptor agonist that carries the generic name Pramipexole.
Mechanism of Action:
The action of this drug is unknown. But it is thought to stimulate the dopamine D2 receptors in the striatum because of its non-ergot-derivative dopamine receptor agonist effect.
Indication:
This medication is used to treat the signs and symptoms of idiopathic Parkinson’s disease.
Contraindications:
This medication is not used in patients who have hypersensitivity to the drug or to any of its components.
Side Effects:
Dizziness, dry mouth, headache, nausea, drowsiness, loss of appetite, stuffy nose, and increased sweating are the common side effects Mirapex.
Adverse Reactions:
Urinary frequency, joint or muscle pain, somnolence, hallucinations, vision changes, difficulty in swallowing and orthostatic hypotension are the possible adverse reactions of this drug.
Cautions:
Use cautiously in patients who have renal impairment or those who are still breastfeeding although the effect in lactation is still unknown.
Important Reminders:
• Advise the patient to take drug with food if nausea develops.
• Instruct the patient not to stop taking the drug abruptly without the doctor’s knowledge. If drug must be stopped, he’ll be required to withdraw from the drug gradually for a week.
• Tell patient to use caution before taking Mirapex with other CNS depressants.
• Instruct the patient not to rise rapidly after sitting or lying down because of risk of dizziness.
• Advice the patient to avoid driving vehicles or avoid hazardous tasks for this drug could cause dizziness.
• Tell the patient that it may take 4 weeks for effects of drug to be noticed because of slow adjustment schedule.
• Tell patients, especially the elderly patients, that hallucination may occur.
• Instruct the female patient to notify prescriber if she is breastfeeding or intends to do so.
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