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Reasons Femara is used and important information about this medication
Breast cancer is a debilitating disease that disables millions of families worldwide. Treating the condition in its early stages has been shown to save a lot of women from possible mortality. For postmenopausal women who have breast cancer, this kind of therapy is possible in the form of Femara, the brand name of Letrozole. It is indicated for early breast cancer patients starting on initial adjuvant therapy. It is the only aromatase inhibitor aside from tamoxifen proven to significantly reduce the early risk of distant metastases.
It is also indicated for extended adjuvant treatment of hormone-dependent breast cancer in women who have started standard adjuvant tamoxifen therapy for 5 years. Aside from use in postmenopausal women who have early breast cancer, it can also be used in those who have advanced breast cancer, and have been previously treated with the use of anti-estrogens.
Indications and Contraindications:
Femara is easy and convenient to use as it is taken as a once-daily tablet at any time of the day you are comfortable with. The recommended dose is one 2.5 mg tablet to be taken with or without meals. It can be taken with other medications such as cimetidine, warfarin, and other commonly prescribed drugs. Another benefit of the drug is that no dose adjustment is necessary for those who have mild to moderate hepatic impairment, renal impairment, and in elderly patients.
For those starting with therapy, use should be continued for 5 years or until tumor relapse occurs. In those who have had tamoxifen therapy, duration of treatment is about 4 years. For those who have advanced or metastatic disease, treatment should continue until tumor progression is seen. Femara cannot be used in people who have hypersensitivity to the drug or its ingredients. Likewise it cannot be used by pregnant and breastfeeding mothers.
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