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Reasons Manerix is used and important information about this medication
Manerix is an antidepressant medication. This is a reversible inhibitor of monoamine oxidase inhibitor type A (RIMA).
This medication is used for the symptomatic relief of depressive illness. This is not recommended to be given in patients who have hypersensitivity to the drug or to any of its components and in children. This is also not recommended to be given to patients who have the following conditions: schizophrenia and schizo-affective disorders, acute states of confusion, and pheochromocytoma (tumor of the adrenal gland).
This medication is used cautiously in patients who have severe decreased liver function, bipolar disorder (manic episodes), agitated and excited states, and thyrotoxicosis.
Manerix involves the selective, reversible inhibition of monoamine oxidase type-A. The inhibition of this substance leads to a reduced metabolism and destruction of monoamines (serotonin, dopamine, and norepinephrine) in the neurotransmitters. This yields in an increase monoamines that relieve depression.
Dizziness, headache, dry mouth, nausea, vomiting, diarrhea, constipation, paresthesias, and disturbed sleep are the most common side effects of this medication. Rash, itch, agitation, somnolence, visual disturbances, confusion, and edema are the possible serious effects of this medication.
Advise the patient to take Manerix exactly as prescribed by the physician. He may take this medication with meals or after meals. Instruct the patient to avoid consuming foods which are rich in amino acid tyramine throughout the treatment with this medication. Tyramine, when taken with this medication could cause a dangerous increase on the blood pressure. Examples of tyramine-rich foods are cheese, yeast extracts, and fermented soy products (example is soy sauce). Instruct the patient not to stop taking this drug abruptly without notifying his physician to prevent withdrawal symptoms. Alcohol intake throughout the therapy must be avoided because this substance could increase the side effects of this drug. Tell the patient to avoid driving and other potentially hazardous activities that require mental alertness until drug’s CNS effects are known.
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