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Reasons Tazorac is used and important information about this medication
Tazorac Cream is classified as a topical antipsoriatic drug. This medication is used to treat mild and severe psoriasis. This medication is also used to treat acne and photodamage. This medication is not used in patients who are hypersensitive to the drug. It is also not used in pregnant women and children 12 years old and below.
In psoriasis, the precise action of this drug is not clearly defined but it is thought that the application of topical tazarotene inhibits the production of epidermal ornithine decarboxylase activity. This is associated with the cell proliferation and hyperplasia. It suppresses the expression of MRP 8 (an inflammatory marker present in psoriatic epidermis at high levels). In acne, this medication is believed to normalize the keratinization and reduce the coherence of follicular keratinocytes. This will result to a comedolytic effect against the present comedones and will prevent the development of new microcomedones.
Itching, dry skin, redness, irritation, burning or stinging sensation, and pain at the site of application are the common side effects of Tazorac Cream. Rash, swelling of the tongue, swelling of the throat, facial edema, severe dizziness, photosensitivity, and difficulty of breathing are the possible adverse reactions to this drug. In using this drug, we have to advise the patient that Tazorac Cream should not be used in eczematous skin. This topical medication must be applied on the psoriatic lesions or acne and not in the normal skin using a clean technique. You have to inform the patient the side effects and adverse reactions of this topical medication and tell them to notify their health care provider if there are any abnormal findings. You also have to instruct the patient to apply sunscreen lotion and use protective clothing when going outside to prevent sensitivity to the sun.
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