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Captopril information for people that are required to take this medicine
Captopril is the first drug developed under the wide category of ACE inhibitors. It can be used as a prophylactic treatment to prevent kidney impairment due to high blood pressure and diabetes mellitus. Captopril can also be used for left ventricular impairment after a myocardial attack. Some of the other ACE inhibitors include enalapril, quinapril, ramipril, fosinopril, benazepril, moexipril and trandolapril.
Drug to Drug interactions:
It is not advisable to use ACE inhibitors with potassium supplements, salt substitutes and diuretics like spironolactone because this will further increase potassium levels in the blood, and may eventually lead to hyperkalemia. During the treatment, regular blood chemistry is done to monitor the potassium level of the patient. Other chemicals that may have an interaction with ACE inhibitor include lithium. There is an unknown reason for an increase in lithium in the blood when taking ACE inhibitors and may eventually lead to lithium toxicity. Aspirin and NSAIDs are also contraindicated as these may decrease the potency of ACE inhibitors.
Contraindications:
It is contraindicated with pregnant women in their second and third trimesters. It should not be used by nursing mothers as the drug can be secreted unto the breast milk. It is also contraindicated to people allergic to the components of the drug. Adjustments must be made by the doctor prior to administering the drug to people with renal impairments.
Side Effects:
Captopril is generally a tolerable medication. One of the distinct side effects of all ACE inhibitors is the presence of a dry, persistent cough. It usually resolves after therapy. Other side effects include abdominal pain, constipation, diarrhea, rash, dizziness headache, loss of taste, loss of appetite, fainting, numbness, and tingling in the hands and feet.
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