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Drug Info, Side Effects and Mestinon taking information for our customers
Manufactured by Valeant Pharmaceuticals, Mestinon prevents the destruction of acetylcholine, being a cholinesterase inhibitor. This makes this medicine an effective treatment to neuromuscular disease called myasthenia gravis. This ailment is characterized by varying degrees of decrease in muscular strength. Clinical trials related to this drug are also being conducted, and one foremost experiment shows that this medicine decreases T cell over activation in HIV infected patients.
For dosage and administration, Mestinon is available in three prescribed packaging and forms:
Syrup — raspberry-flavored liquid, containing 60 mg Pyridostigmine bromide per teaspoonful (5 mL). This is particularly convenient to administer among very young patients because it is easier to swallow. Accurate dosage is easily dispensed to myasthenia patients who require adjusted doses.
Conventional Tablets — each tablet contains 60 mg Pyridostigmine bromide. This form provides gradual release, prolonging the drug efficacy. This extended process regulates myasthenia symptoms.
The average dosage is ten 60 mg tablets or ten 5ml teaspoonfuls a day for syrup and conventional tablet. In more serious cases, 25 tablets or teaspoonfuls maybe required while in mild cases, one to six tablets a day is adequate. For time span tablets, one to three 180 mg tablets, twice daily is generally sufficient to control symptoms. Dosage interval is at least every six hours.
There are very few reports of side effects, some minor reactions maybe experienced like nausea, vomiting, diarrhoea, abdominal cramps, increased peristalsis, increased salivation, increased bronchial secretions, meiosis and diaphoresis. It is also possible to feel muscle cramps, fasciculation and weakness but this usually subside upon discontinuance of the medication.
Patients with other medical conditions especially lung problems must take precautionary measures. And since Mestinon contains sugar, diabetics should also seek consultation prior to taking this drug. Safety in pregnant and lactating patients has not also been established.
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