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Drug Info, Side Effects and Monopril taking information for our customers
Monopril sodium is a widely available drug that has many functions. It inhibits angiotensin converting enzyme, prevents conversion of angiotensin I to angiotensin II, and dilates blood vessels. It works by decreasing the amount of angiotensin II in the body, which eventually decreases peripheral arterial resistance. The total action results to a low blood pressure. Monopril indirectly decreases aldosterone secretion, reducing sodium production as well as preventing water retention.
Indication and Dosage:
• The recommended dose of the tablets is around 10 mg to be taken once a day, either when used alone or added to another drug such as a diuretic
• However, the dosage range can increase to 20 to 40 mg, and a maximum dose of 80 mg.
• For children, a dose of 0.1 to 0.6 mg/kg can reduce blood pressure.
• For people diagnosed with heart failure, an initial dose of 10 mg once daily should be given. The dosage can be increased weekly to a dose that is well tolerated, and should not exceed around 40 mg once daily.
Contraindications:
• Hypersensitivity to drug components
• People with renal impairments, and those who have autoimmune diseases
• Pregnant women in their second and third trimesters
Adverse Effects:
• dizziness, fainting, headache, malaise, fatigue, and fever
• tachycardia, hypotension, and angina
• abdominal pain, anorexia, constipation, diarrhea, dry mouth, nausea, and vomiting
• agranulocytosis
• hyperkalemia (increased potassium levels)
• dry persistent non-productive cough, dyspnea
• balding and loss of hair
• itchiness
Considerations:
Always check blood pressure to assess effectiveness. Monopril must be taken one hour before meals. Food in the stomach may decrease absorption of the drug. Drink plenty of water to prevent lightheadedness. Remind patient that lightheadedness may be felt in the first few days of therapy. Caution is necessary in elderly people because they are more prone to hypotension.
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