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Medical examinations and physical examinations should be done prior to starting a patient on Persantine therapy. All the past and present medical conditions of the patients should be evaluated carefully in order to determine the safety of Persantine to the patient.
The physician should assess the patient for diseases or medical conditions that may affect the success of Persantine treatment regimen. The patient’s liver should be assessed for liver cirrhosis or hepatitis. Reports have been noted wherein patients being treated with Persantine have experienced an elevation in their hepatic enzymes with subsequent hepatic failure. Patients suffering from liver disorders should be given Persantine with caution.
The patient’s cardiovascular status must also be evaluated before the patient undergoes heart valve transplant surgery, making sure that the patient does not have low blood pressure, uncontrolled chest pain or angina, coronary artery disease and uncontrolled chest pain or angina. These conditions may worsen if the patient takes Persantine postoperatively to prevent blood clots. These conditions may generally worsen because of the ability of Persantine to cause vasodilation, or an increase in the diameter of blood vessels. These conditions may become worse and become life threatening if the patient is not evaluated right away.
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