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Drug Info, Side Effects and Viokase taking information for our customers
Pancrelipase tablets are available under the brand name Viokase. It contains a pancreatic enzyme concentrate of porcine origin, which is derived from pigs. It contains standardized lipase, protease, and amylase, which are pancreatic enzymes. Viokase is used for the treatment of exocrine pancreatic insufficiency. Conditions characterized by the lack of pancreatic enzymes include cystic fibrosis, chronic pancreatitis, pancreatectomy, and obstruction of the pancreatic ducts.
The brand Viokase is available in both tablet and powder dosage form, which are meant for oral administration. The powder dosage form can be used by people who have difficulty swallowing, and can be mixed with a spoonful of food for better administration. It must be taken with meals as the digestive capacity of the enzyme concentrate depends primarily on the amount that enters through the stomach and available in the intestine.
It cannot be used by patients who have known hypersensitivity to pork proteins, trypsin, pancreatin, or pancrelipase. Do not hold the medication in the mouth as it may cause irritation of the mucosa. This is perhaps one of its most noted adverse effects. The pancreatic enzyme is manufactured to a fine powder finish, which can irritate the nasal mucosa and the respiratory tract. Inhalation of this proteolytic enzyme may even cause an asthma attack. Toxicity or extremely high doses of pancreatic enzymes can be associated to conditions such as increased uric acid levels in the blood and urine. Over dosage can also cause diarrhea, or transient intestinal upset.
Around a fourth of a teaspoon is administered for patients with cystic fibrosis. It can also range from one to four Viokase tablets with meals as directed by a competent health care provider. For patients who no longer have pancreas, or obstruction of the pancreatic ducts, around one to two tablets are taken at an interval of two hours.
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