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Drug Info, Side Effects and Zyloprim taking information for our customers
Zyloprim is the brand name of allopurinol, an agent used to lower the uric acid level in the blood. Allopurinol reduces the production of uric acid (a chemical created when the body breaks down purines) in the body. Purines are found on some foods and drinks like anchovies, liver, mackerel, peas and dried beans, wine and beer. If uric acids are created too much by the body, or are not eliminated from the body, it can accumulate in the blood causing hyperurecemia (increased level of urates) and gouty arthritis—a form of arthritis that causes swelling and severe pain in the joints. The commonly affected body part is the big toe but it may also affect the hand, wrist, elbow, heel and ankle. Uric acid maintained at high levels may also bring about kidney stones.
Drug Interactions:
• Theophylline derivatives—when simultaneously used with Zyloprim, the action of these drugs may be increased and may allow theophylline toxicity to occur. One should observe the following symptoms: vomiting, dizziness, restlessness and cardiac arrhythmias.
• Chlorpropamide—Zyloprim may reduce the metabolism of chlorpropamide. If you currently have an increased level of blood sugar and is taking oral hypoglycemic agents (drugs that lower down blood glucose) to counter it, you may need to have the dosage adjusted. Signs of hypoglycemia (low blood glucose) include headache, weakness, decreased coordination, general apprehension, increased perspiration, hunger, and blurred or double vision.
• You should start with one third or one fourth of the usual dose and you should have your doctor adjust the succeeding dosage according to your response with the treatment.
• Cyclophosphamide—there is a high incidence of bone marrow depression (bone marrow is the flexible tissue found in the cavity of bones—middle part. It is intended to produce new blood cells necessary for our body to function well.
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