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Chloramphenicol drug description and what Chloramphenicol is used to treat
Chloramphenicol is a systemic anti-infective drug. It is an antibiotic used to treat serious infections caused by bacteria such as Salmonella, H. Influenzae, rickettsiae, and other gram-negative germs. It works by slowing the growth of infective microorganisms. It is usually used only when less potentially dangerous drugs are proven to be ineffective. It works by binding to bacteria and inhibiting protein synthesis.
Indications and Contraindications:
The drug is commonly used to treat acute infections caused by Salmonella typhi. It can also be used in the treatment of cystic fibrosis. If you have a history of hypersensitivity to Chloramphenicol, or any other antibiotic in general, it is imperative that you first consult your doctor. This drug is so potent that it cannot be used to treat trivial infections, or those that are not indicated. Wrong use of this medication may lead to various blood problems such as leukemia, anemia, low blood platelets, low white blood cell counts, and bone marrow depression. Common side effects such as nausea, vomiting, and mild diarrhea have been reported. Because of some undesirable consequences, this drug can’t be used for simple infections like colds, coughs, flu, and throat infections.
Warning is given to pregnant patients as the medicine can easily cross the placental barrier. Do not use barbiturates, rifampin, anticoagulants, penicillins, sulfonylureas, iron salts, cyclophosphamide, and vitamin B12 as these may affect the action of Chloramphenicol. If inflammation of the gums, headache, mild depression, mental confusion, fever, rashes, itchiness, and eye problems are experienced, immediately stop taking the medication and consult your doctor.
Chloramphenicol is usually administered through the vein. It is available through an injection which is performed at a health care institution by a licensed practitioner. It can be used at home if procedures are taught by a competent health care provider. Do not administer the medication if the vial is cracked or damaged.
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