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In several medium term genetic toxicity tests, Clindamycin was positive in approximately 1 of 7 strains used in bacterial reverse mutation assays; Salmonella strain TA102. This medication was positive in mammalian cell mutation and chromosome aberration assay evaluations. This medication was positive in unscheduled DNA synthesis in rat hepatocytes but not in human leukocytes. Clindamycin was negative in micronucleus tests in mice, cytogenetics test in rats, and also DNA repair test in rats. The findings could possibly be due to the inhibitory effects of elevated concentrations on eukaryotic type II DNA topoisomerase.
Before taking this medication, be sure you tell your doctor or pharmacist or health care provider if you are allergic to any type of medication. This medication may contain inactive or inert ingredients, which may cause allergic reactions or other problems. Talk to your doctor or pharmacist or health care provider for more details concerning this medication. It is critical that you be sure to advise your doctor and pharmacist precisely what prescription and non-prescription medications, any vitamins, as well as nutritional supplements, and even over the counter and herbal products you are taking or may plan to take while using this treatment.
Remember that your doctor, pharmacist, or health care professional has prescribed Clindamycin because he or she has judged that the possible benefit to you is greater than the possible risk of side effects. Many, but not all, people using this treatment method do not have, and have not had, serious side effects. Most people who decided to use this treatment option found it to be moderately to highly effective in relieving the ocular pressure issues associated with infections. As you continue this treatment plan, if any of these effects persist or worsen at any time, tell your doctor, pharmacist, or health care professional promptly.
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