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Colchicine information for people that are required to take this medicine
Colchicine is approved for the treatment of gout -a condition characterized with the swelling or inflammation of joints as uric acid crystals form deposits on those parts of the body. Though it has been proven to gout, lessens attacks to Familial Mediterranean fever (FMF) patients, and inhibits mitosis to cancer patients, it’s no excuse for some side effects.
Because of the drugs toxicity, it is highly not recommended for patients with acute renal insufficiency. Its side effects appear within 24- hour span. Symptoms become visible after two to five hours after the ingestion. Common minor symptoms include throat, mouth and abdominal pain, as well as vomiting associated with fever and may lead to kidney failure. Worse, high dosage distracts the proper functioning of the bone marrow and would eventually result to anemia.
Patients who are undergoing Colchicine treatment is highly advised NOT to take grapefruit or grapefruit juice because it heightens the serum concentration present in it. Myopathy, multiple organ dysfunctions (MOD), pancytopenia and neuropathy are the leading effects of the intake of this drug when taken with the grapefruit or grapefruit juice.
It is also highly not recommended for patients aged 2 years old or below. Also, do not take the drug if you are pre-diagnosed to having kidney problems or currently undergoing series of dialysis. Honestly tell the doctor that you are having bowel problems, periodic stomach aching, heart failure issues, or you have poor health condition in general. For pregnant women or women who are planning to conceive a baby or women who are currently breastfeeding, it is also important to tell your doctor since dosage of Colchicine might incur a negative effect to the unborn child. Telling your doctor your condition is of paramount importance to avoid further complications. This is a precautionary measure to every patient.
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