DESIPRAMINE DESCRIPTION

Desipramine Hcl (generic of Norpramin) - Tablet

Desipramine Hcl is manufactured by Apotex. This medicine is a tricyclic antidepressant used to treat depression. It may also be used to treat other conditions as determined by your doctor.

Where can I order Desipramine From? Can I buy Desipramine at Canadian Prices?

Yes, if you are from the U.S. then you can buy Desipramine at Canadian prices. Currently we will only accept an order for Desipramine from U.S. and Canadian residents. Both U.S. and Canadian residents require a prescription to purchase Desipramine and when you order Desipramine it will be delivered with express shipping.

Why is Desipramine drug prescribed?

Desipramine is used in the treatment of depression. It is one of a family of drugs called tricyclic antidepressants. Drugs in this class are thought to work by affecting the levels of the brain's natural chemical messengers (called neurotransmitters), and adjusting the brain's response to them.

Desipramine has also been used to treat bulimia and attention deficit disorders, and to help with cocaine withdrawal.

Most important fact about Desipramine

Serious, sometimes fatal, reactions have been known to occur when drugs such as Desipramine are taken with another type of antidepressant called an MAO inhibitor. Drugs in this category include Nardil and Parnate. Do not take Desipramine within two weeks of taking one of these drugs. Make sure your doctor and pharmacist know of all the medications you are taking.

How should you take Desipramine?

Desipramine should be taken exactly as prescribed. Do not stop taking Desipramine if you feel no immediate effect. It can take up to 2 or 3 weeks for improvement to begin. Desipramine can cause dry mouth. Sucking hard candy or chewing gum can help this problem. --If you miss a dose...If you take several doses per day, take the forgotten dose as soon as you remember, then take any remaining doses for the day at evenly spaced intervals. If you take Desipramine once a day at bedtime and don't remember until morning, skip the missed dose. Never try to "catch up" by doubling the dose. --Storage instructions...

Desipramine can be stored at room temperature. Protect it from excessive heat.

What side effects may occur with Desipramine?

Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Desipramine.

Side effects may include:
Abdominal cramps, agitation, anxiety, black tongue, black, red, or blue spots on skin, blurred vision, breast development in males, breast enlargement in females, confusion, constipation, delusions, diarrhea, dilated pupils, disorientation, dizziness, drowsiness, dry mouth, excessive or spontaneous flow of milk, fatigue, fever, flushing, frequent urination or difficulty or delay in urinating, hallucinations, headache, heart attack, heartbeat irregularities, hepatitis, high or low blood pressure, high or low blood sugar, hives, impotence, increased or decreased sex drive, inflammation of the mouth, insomnia, intestinal blockage, lack of coordination,light-headedness (especially when rising from lying down), loss of appetite, loss of hair, mild elation, nausea, nightmares, odd taste in mouth, painful ejaculation, palpitations, purplish spots on the skin, rapid heartbeat, restlessness, ringing in the ears, seizures, sensitivity to light, skin itching and rash, sore throat, stomach pain, stroke, sweating, swelling due to fluid retention (especially in face or tongue), swelling of testicles, swollen glands, tingling, numbness and pins and needles in hands and feet, tremors, urinating at night, visual problems, vomiting, weakness, weight gain or loss, worsening of psychosis, yellowed skin and whites of eyes

Possible food and drug interactions when taking Desipramine

People who take antidepressant drugs known as MAO inhibitors (including Nardil and Parnate) should not take Desipramine. If Desipramine is taken with certain other drugs, the effects of either could be increased, decreased, or altered. It is especially important to check with your doctor before combining Desipramine with the following:

Cimetidine (Tagamet)
Drugs that improve breathing, such as Proventil
Drugs that relax certain muscles, such as Bentyl
Fluoxetine (Prozac)
Guanethidine (Ismelin)
Paroxetine (Paxil)
Sedatives/hypnotics (Halcion, Valium)
Sertraline (Zoloft)
Thyroid medications (Synthroid)

Extreme drowsiness and other potentially serious effects can result if Desipramine is combined with alcohol or other depressants, including narcotic painkillers such as Percocet and Demerol, sleeping medications such as Halcion and Nembutal, and tranquilizers such as Valium and Xanax.

Special information if you are pregnant or breastfeeding when taking Desipramine

Pregnant women or mothers who are nursing an infant should use Desipramine only when the potential benefits clearly outweigh the potential risks. If you are pregnant or planning to become pregnant, inform your doctor immediately.

Recommended Desipramine dosage

Your doctor will tailor the dose to your individual needs.

ADULTS The usual dose ranges from 100 to 200 milligrams per day, taken in 1 dose or divided into smaller doses. If needed, dosages may gradually be increased to 300 milligrams a day. Dosages above 300 milligrams per day are not recommended.

CHILDREN Desipramine is not recommended for children.

OLDER ADULTS AND ADOLESCENTS The usual dose ranges from 25 to 100 milligrams per day. If needed, dosages may gradually be increased to 150 milligrams a day. Doses above 150 milligrams per day are not recommended.

Desipramine Overdosage

Any medication taken in excess can have serious consequences. An overdosage of Desipramine can be fatal. If you suspect an overdose, seek medical help immediately.

Symptoms of overdose may include:
Agitation, coma, confusion, convulsions, dilated pupils, disturbed concentration, drowsiness, extremely low blood pressure, hallucinations, high fever, irregular heart rate, low body temperature, overactive reflexes, rigid muscles, stupor, vomiting

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