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Doxepin information for people that are required to take this medicine
Doxepin hydrochloride belongs to a drug class known as tricyclic antidepressants. It is primarily indicated for the treatment of the symptoms brought about by clinically significant depression and anxiety. It is also indicated for the treatment of anxiety and depression of conditions such as alcoholism and bipolar disorders. Doxepin works by restoring the balance of neurotransmitters in the body by increasing the levels of available serotonin and norepinephrine. It has protriptyline that can enervate withdrawn and patients who do not have energy. It can also be used in depression or anxiety previously associated with organic disease. Doxepin is also prescribed for psychotic depressive disorders with anxiety, including involutional depression and manic-depressive disorders. The psychoneurotic symptoms relieved by this drug include anxiety, tension, depression, somatic symptoms and concerns, sleep disturbances, guilt, lack of energy, fear, apprehension, and worry.
Administration and Dosage
In some populations including adolescents, elderly, and outpatients, a low dosage should be initiated, at around 25-75 mg per day. The use of the drug is not recommended for children younger than 12 years of age. Most antidepressants drugs take 10 days to 4 weeks before a therapeutic response is observed. Consumers should know that increasing the dose will not shorten this period, but rather increase the incidence of unwanted adverse reactions. For those who are using Doxepin as maintenance, a therapy of at least 3 months is needed to prevent relapse. Usual dosage is 75 to 150 mg/day. The total daily dosage, up to 150 mg, may be given at one dose, during bedtime. For those who have more severe anxiety or depression, higher doses of 300 mg per day may be prescribed. This drug is not only available in 25, 50, 75, 100, and 150 mg capsules; it is also available in oral concentrates. An oral concentrate should be diluted with around 120 mL or water, milk, or fruit juices except grape fruit prior to administration.
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