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The product Dukoral is used for the following reasons for people

Dukoral is an orally administered vaccine for prevention of cholera (an infection caused by the bacterium Vibrio cholerae that targets the small intestines) and traveller’s diarrhea. It is manifested by continuous watery bowel movement and vomiting. It is transmitted primarily by ingestion of contaminated drinking water or food. First aid treatment uses oral hydration salt solution while antibiotics are administered for severe cases. Mostly affected by this disease are travellers and those who are living in areas with no or limited access to safe drinking water and in poorly sanitized environment.

Dukoral works by introducing a small amount of killed cholera bacteria into the body so it could develop new antibodies or strengthen the immune system against the specified bacteria and toxins. Being a cholera vaccine, it contains killed but previously strong and active micro organisms particularly the V cholera 01.

Administration of Dukoral vaccine along with sanitation is a good preventive measure. It provides limited or temporary protection on the onset of cholera. It has an 85% efficacy with minimal side effects. It is available in suspension form which comes in a single-dose glass vial and supplied with one sachet of sodium hydrogen carbonate (effervescent granules) to be dissolved in a glass of water. Food and liquid intake one hour before and one hour after the administration is not allowed. Also, no other medications should be taken within the specified period. Other factors like body weight and health conditions might affect the efficiency of the vaccine. It can be administered during pregnancy and to breastfeeding mothers.

There are very rare and uncommon reports of headache, loss of appetite, dizziness, abdominal pain and respiratory problems. It is generally has been a well tolerated medication. Over dosage reaction is consistent with the effects after using the recommended dosage.

Precautionary measures should be taken into consideration if patient is suffering from acute gastrointestinal and febrile illness.

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