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Fenofibrate information for people that are required to take this medicine
A great population thrives in foods that can be consumed instantly. Most of the food domineering the market can be consumed by means of frying. Some have great densities of fat contained within them. This, along with a sedentary lifestyle, contributes to high rates of coronary diseases. Men age 45 years or older, and women 55 years or older, those who have family history of heart disease, smokers, diabetics, hypertensive, and obese patients are predisposed to developing different heart ailments.
These factors precipitate the occurrence of atherosclerosis, characterized by extremely dangerous levels of low density lipoprotein or LDL, which is popularly tagged as the bad cholesterol. The recommended diet should have a reduced total dietary fat and saturated fat, increased intake of polyunsaturated fat, and reduced daily cholesterol levels to an acceptable range of 250 to 300 mg. However, this diet modification, as well as other modalities including exercise and weight control may not prove to reap enough benefits. Sometimes, the use of medications is needed for adjunctive therapy. Antihyperlipidemic agents in the form of Fenofibrate may be prescribed.
The use of drugs such as bile acid sequestrants, oral anticoagulants, cyclosporine, and HMG-CoA reductase inhibitors may either potentiate or decrease the effects of Fenofibrate. It is best to avoid these drug unless thoroughly necessary, to avoid prevalence of adverse reactions such as abdominal pain, abnormal liver function tests, back pain, headache, increased ALT and AST, increased creatine phosphokinase, and respiratory disorders.
The use of Fenofibrate requires continuous monitoring. The level of serum lipids upon initiating therapy must be periodically determined, so that the lowest dose possible may be given. This is also done to see the effectivity of the treatment. If within two months of treatment, no adequate response is seen, the use of the drug should be stopped. This is done especially when the enzyme levels persist above 3 times the normal range.
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