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Florinef drug description and what Florinef is used to treat
Florinef is a mineral corticoid that increases sodium re-absorption, potassium and hydrogen secretion at the kidneys.
Indication and Dosages:
• Salt-losing adrenogenital syndrome: 0.1 to 0.2 milligram orally per day
• Addison disease (adrenocortical insufficiency): 0.1 milligram orally
• Postural hypotension: 0.1 to 0.4 milligram daily for diabetic patients,
• 0.05 to 0.2 milligram daily in people with postural hypotension
Contraindication:
The use is contraindicated to persons with systemic fungal infections and known hypersensitivity to the drug. Use cautiously in people with hypothyroidism, recent myocardial infarction , cirrhosis, ocular herpes simplex, emotional instability psychotic tendencies, diverticulitis, fresh intestinal anatomizes, active and latent peptic ulcer, renal/ insufficiency, hypertension, osteoporosis, myasthenia gravis, active hepatitis, active tuberculosis, or non-specific ulcerative colitis. Use cautiously in breast feeding mothers. Persons who are about to take vaccines for smallpox are discouraged from taking the drug along with vaccination.
Interactions:
The use of anabolic steroids and estrogens may increase fludrocortisone levels. Barbiturates, carbamazepine, fospheytoin, may diminish the effect of corticosteroids. Digoxin may increase the risk of digoxin toxicity associated with hypokalemia. The doctor may recommend monitoring of potassium and digoxin levels. Potassium depleting drugs such as amphotericin B and thiazide diuretics may enhance potassium wasting effect; monitoring of potassium levels may be advised. Effectiveness of salicylates may also be decreased with the use of this drug.
Important facts:
• Florinef is used with cortisone or/ hydrocortisone in adrenal insufficiency.
• The drug may cause severe hypoglycaemia.
• Monitor blood pressure because it may cause hypertension.
• Regular electrolyte monitoring because it may affect the electrolytes.
• Monitor weigh daily. Sudden increase in weight gain may be reportable to the doctor.
• Potassium supplement may be needed while taking the medication.
• Symptoms like low blood pressure, weakness, cramping or palpitation worsen or change in mental status, seeking medical attention is needed.
• Mild swelling may be present
• Avoid exposure to infection like smallpox and measles. Notify the doctor if such exposure occurs.
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