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What is Generic Tricor alternative and information for taking this drug
Fenofibrate is an antihyperlipidemic agent. It works be increasing the breakdown of fats, and elimination of triglyceride particles from the blood. This is done through the activation of the enzyme lipoprotein lipase, and reduction of the production of apoprotein C III. The desired action is a fall in the number of triglyceride, and alteration of bad cholesterol known low density lipoprotein.
Administration and Dosage:
Before instituting therapy, lipid levels should be checked for abnormality. It should also be ascertained that methods such as diet, exercise, weight loss, and other means of control have been exhausted and proven ineffective when done without medications. Medications which are known to exacerbate the effects of hypertriglyceridemia such as beta blockers, thiazides, and estrogens should either be discontinued or changed if possible.
The initial dose for hypertriglyceridemia is 48-145 mg per day, up to a maximum dose of 145 mg/day. The usual initial dose for primary hypercholesterolemia or mixed hyperlipidemia is 145 mg/day. The dose may be further adjusted with regard to renal function and geriatric considerations. It can also be adjusted if necessary after determining lipid levels at every 4 to 8 week intervals. The therapy is withdrawn in people who do not exhibit adequate response to therapy after 2 months of continued treatment with the use of the maximum recommended dose.
Contraindications:
The use of Fenofibrate is not for everyone, as those who have liver problems, kidney dysfunction, preexisting gallbladder disease, and known or suspected hypersensitivity to the drug or its components may not benefit entirely from the use of this drug. Although this drug can decrease the level of lipids, Fenofibrate may increase cholesterol excretion into the bile. This can lead to a condition known as cholelithiasis. The therapy must be discontinued when gallstones are formed.
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