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Letrozole information for people that are required to take this medicine
Letrozole Used in Treating Female People With Breast Cancer is commonly prescribed for the treatment of both early and advanced stages of breast cancer. It belongs to a class of drugs known as aromatase inhibitors. It works by preventing aromatase, decreasing production of the hormone estrogen. By doing so, it helps the pituitary gland produce hormones needed to stimulate ovulation. Recently, it has been added to the list of drugs used for treatment of infertility.
It can be used to induce an egg to develop and be released in women who are not capable of ovulation. It can also be used to increase chances of pregnancy in women who have no problems in ovulation. As a fertility medication, Letrozole is used prior to pregnancy. There is a distinction when used during pregnancy, as it can cause birth defects.
Studies have shown that pregnancy rates with the use of Letrozole have surpassed that of the rates with the use of Clomid and Gonadotropin. These were previously used for infertility treatment. This medication works by reducing estrogen levels. However, low estrogen levels can bring about symptoms such as hot flushes, headaches, and breast tenderness. These are also the same symptoms when you use other forms of treatment such as Clomid or Gonadotropin.
Unlike when used for breast cancer therapy, Letrozole for infertility is only used for 5 days. The usual dose for ovulation induction is 2.5 mg. Although single doses around 60 mg have shown no detrimental effects, do not take more than the recommended dose. No dose adjustment is necessary for those who have mild to moderate hepatic impairment, renal impairment, and in elderly patients. Do not under dose or over dose. If you happen to miss a dose, take it as soon as you remember to. Do not double your dose to make up for the missed medication.
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