Sinemet is an antidyskinetic combination used to treat Parkinson's disease. This medicine may also be used to treat other conditions as determined by your doctor.
Why is this Levodopa prescribed?
Levodopa CR is a controlled-release tablet that may be given to help relieve the muscle stiffness, tremor, and weakness caused by Parkinson's disease. It may also be given to relieve Parkinson-like symptoms caused by encephalitis (brain fever), carbon monoxide poisoning, or manganese poisoning.Levodopa CR contains two drugs, carbidopa and levodopa. The drug that actually produces the anti-Parkinson's effect is levodopa. Levodopa prevents vitamin B6 from destroying levodopa, thus allowing levodopa to work more efficiently.
Parkinson's drugs such as Levodopa CR relieve the symptoms of the disease, but are not a permanent cure.
Where can I order Levodopa from? Can I buy Levodopa
at Canadian Prices?
Yes, if you are from the U.S. then you can
buy Levodopa at Canadian prices. Currently we will only accept
an order for Levodopa from U.S. and Canadian residents. Both
U.S. and Canadian residents require a prescription to purchase
Levodopa and when you order Levodopa it will be delivered with
express shipping.
How should you take Levodopa?
Take Levodopa CR after meals, rather than before or between
meals. Swallow the tablets whole without chewing or crushing
them.Levodopa CR releases its ingredients slowly over a period
of 4 to 6 hours. It is important to follow a careful schedule,
taking your doses at the same time every day.You should not
change the prescribed dosage or add another product for Parkinson's
disease without first consulting your doctor.Levodopa CR works
best when there is a constant amount in the blood. Try not
to miss any doses, and take them at evenly spaced intervals
day and night.--If you miss a dose...If you forget to take
a dose, take it as soon as you remember. If it is almost time
for your next dose, skip the one you missed and go back to
your regular schedule. Do not take 2 doses at once.--Storage
instructions...
Store at room temperature in a tightly closed container.
What side effects may occur?
Side effects from Levodopa CR cannot be anticipated. If any develop or change in intensity, inform your doctor immediately.Only your doctor can determine if it is safe for you to continue taking Levodopa CR.
More common side effects may include:
Confusion, hallucinations, nausea, uncontrollable twitching
or jerking
Less common or rare side effects may include:
Abdominal or stomach pain, abnormal dreams, agitation, anemia,
anxiety, back pain, bizarre breathing patterns, bleeding from
stomach, blisters, blurred vision, burning sensation of tongue,
chest pain, clumsiness in walking, common cold, constipation,
convulsions, cough, dark saliva, dark sweat, dark urine, delusions,
depression, diarrhea, dilated pupils, disorientation, dizziness,
dizziness upon rising from a sitting or lying position, double
vision, dream abnormalities, drooling, drowsiness, dry mouth,
euphoria, eyelid twitching, faintness, falling, fatigue, fever,
flatulence, fluid retention, flushing, hair loss, headache,
heart attack, heart palpitations, heartburn, hiccups, high
or low blood pressure, hoarseness, hot flashes, increased
sex drive, increased tremor, insomnia or other sleep problems,
irregular heartbeat, leg pain, locked jaw, loss of appetite,
malignant melanoma, memory problems, mental changes, muscle
cramps, muscle twitching, nervousness, numbness, "on-off"
phenomena, paralysis of certain muscles and unwanted movement
of others, paranoia, persistent erection, phlebitis (swelling
of a vein), rash, rolling eyes, shortness of breath, shoulder
pain, slowed physical movements, sore throat, speech impairment,
stomach ulcer, suicidal tendencies, swallowing difficulties,
sweating, taste changes, teeth-grinding, tingling or pins
and needles, upper respiratory infection, upset stomach, urinary
frequency, urinary incontinence, urinary retention, urinary
tract infections, weakness, weight loss or gain, writhing
or flailing movements, vomiting
Recommended dosage
Your doctor will tailor your individual dosage carefully, depending on your response to previous therapy and symptoms.
ADULTS
For patients with mild to moderate symptoms, the initial recommended dose is 1 tablet of Levodopa CR taken 2 times a day.
Starting doses should be spaced out every 4 to 8 hours and then adjusted to each patient's individual response.The usual long-term dose is 2 to 8 tablets per day, taken in divided doses every 4 to 8 hours during the waking day.Higher doses (12 or more tablets per day) and shorter intervals (less than 4 hours) have been used, but are not usually recommended.When doses of Levodopa CR are given at intervals of less than 4 hours, and/or if the divided doses are not equal, it is recommended that the smaller doses be given at the end of the day.An interval of at least 3 days between dosage adjustments is recommended.Dosage adjustment of Levodopa CR may be necessary if your doctor prescribes additional medications.
CHILDREN
Use of Levodopa CR in children under 18 is not recommended.
Overdosage
Too much Levodopa CR may cause muscle twitches, inability to open the eyes, or other symptoms of levodopa overdosage. Like other medications, Levodopa CR taken in excess can have serious consequences. If you suspect symptoms of a Levodopa CR overdose, seek medical attention immediately.
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