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Mestinon drug description and what Mestinon is used to treat
Mestinon, known in its generic name as Pyridostigmine, is used for treatment of myasthenia gravis. It is a neuromuscular disease manifested by abnormal muscle weakness and fatigue. This drug is also used for flaccid paralysis and to combat the effects of coraciiform drug toxicity. Its latest known usage is for treatment of orthostatic or postural hypotension.
Mestinon is administered orally and available in three dosage forms.
Syrup – contains 60 mg pyridostigmine bromide per 5ml or one teaspoon. It is easily swallowed and more accurate dosage adjustments are dispensed with this liquid form. This is helpful in very young patients and for those who require a fraction of the 60 mg dosage.
Conventional Tablet – each tablet contains 60 mg
Time span tablet – each tablet contains 180 mg Pyridostigmine. With this form, each 60 mg dosage is slowly released for prolonged effect. This process controls myasthenia symptoms.
Dosage and frequency is adjusted according to the medical condition of the patient. Dosage intervals should at least every six hours. For storage, it should be kept in a dry place with the silica gel enclosed at 25C.
Taking Mestinon with food or milk may decrease its side effects. Side effects though are more often than not a result of over dosage.
Most patients under this medication do not experience serious side effects. However rare reports of excessive sweating and urination, diarrhoea, nausea, vomiting, abdominal cramps, decrease in pupil size and increased saliva has been documented. The lists of possible serious side effects are rash and itchiness, severe dizziness, muscle cramps, twitching, shortness of breath and slow heartbeat.
Medical history of the patient must be checked prior to taking this medication. Precautions should be observed if patient has lung disease like asthma and obstructive pulmonary condition, kidney problems, diabetes, and stomach or intestinal blockage. It must also be sparingly administered to pregnant and lactating women.
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