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Methazolamide information for people that are required to take this medicine
Methazolamide is the generic name marketed under brand names Glauctabs, MZM, and Neptazane. Methazolamide is both a Sulfonamide derivative and a carbonic anhydrase inhibitor. It functions to reduce the amount of the enzyme carbonic anhydrase. This enzyme is responsible for increasing the amount of aqueous humor produced within the eye.
Methazolamide then reduces the amount of fluid produced in the eyes leading to a decrease in intraocular pressure. An increase in fluid leads to increase in optic pressure, leading to the symptoms of Glaucoma such as blurred vision, halos around white lights, pain in the forehead and in the orbital area. It can also be used for other conditions that are caused by a high intraocular pressure, such as chronic open-angle glaucoma, and secondary glaucoma. The drug has been proven helpful in cases of acute angle glaucoma as well. It is usually used in acute angle-closure glaucoma where low pressure in the eye is needed to reduce risks during surgery.
Precautions:
As with most drugs, consumption is generally not advisable for pregnant and nursing mothers. It is contraindicated to those who are taking aspirin, salicylates, cyclosporine, quinidine, phenytoin, amphetamine, sodium bicarbonate, primodone, lithium, methenamine, and other Carbonic anhydrase inhibitors as part of their therapy. If you have a history of adrenal gland failure, kidney disorders, or liver diseases such as cirrhosis and hepatic encephalopathy, this drug is not for you. It cannot be used when sodium or potassium blood levels are decreased, or when there are other electrolyte problems. Potassium excretion has been reported to increase upon initial therapy. Taking this drug altogether may lead to hypokalemia.
After taking the drug the patient should tell the doctor if he or she experiences:
• fatigue
• loss of appetite
• taste alteration
• stomach upset
• hearing dysfunction
• drowsiness
• confusion
• rashes
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