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Microzide drug description and what Microzide is used to treat
Microzide is a potent thiazide diuretic than can effectively excrete excessive salt in the body including water. It is an effective drug used to treat patients suffering from congestive heart failure, hypertension, liver cirrhosis, kidney impairment, and edema brought about by steroid and estrogen therapy.
Microzide acts by blocking the reabsorption of sodium and chloride in the kidneys. Along with sodium and chloride, water is also being excreted through the kidneys. Microzide also increases potassium and hydrogen ion excretion. On the other hand, calcium and uric acid are retained. This action of Microzide may cause a massive electrolyte imbalance in the body.
This mechanism of action caused by Microzide greatly benefits patients suffering from congestive heart failure since this drug can excrete the excessive amounts of water in the patient’s body. This in turn decreases the patient’s blood volume which makes the weak heart pump blood more effectively throughout the body. In patients with liver cirrhosis, accumulation of fluid in the patient’s abdomen occurs, most commonly known as ascites. Microzide can aid decrease the amount of fluid retained in patients with ascites. Patients with edema benefit from this same action of Microzide. Excessive amounts of fluid retained in the interstitial spaces of the patient’s body are excreted through the kidneys.
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