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Minocycline information for people that are required to take this medicine
Minocycline is a tetracycline analog, having a 7-dimethylamino and lacking the 5 methyl and hydroxyl groups, which is effective against tetracycline-resistant staphylococcus infections.
This medication is used to treat: infections caused by susceptible gram-negative and gram-positive organisms (including Haemophilus ducreyi, Yersinia pestis, and Campylobacter fetus), Rickettsiae species, Mycoplasma pneumonia, and Chlamydia trachomatis; psittacosis; granuloma inguinale; syphilis in patients allergic to penicillin; gonorrhea in patients allergic to penicillin; meningococcal carrier state; and acne.
This medication may be bacteriostatic by binding to the microoraganism’s ribosomal subunits, inhibiting protein synthesis. It may also alter the cytoplasmic membrane of susceptible microorganisms.
Minocycline should not be given in children younger than age 8 for it may cause discoloration of teeth, enamel defects, and retarded growth. A woman who has intentions of getting pregnant but has an infection should inform her health care provider because this drug can cause a possible teratogenic effect.
Nausea, vomiting, and diarrhea are the most common side effects of this drug.
For patients with renal or hepatic diseases, this drug should be given cautiously. Monitor their renal and liver function test results.
In giving Minocycline, advise the patient to take the drug exactly as prescribed by the doctor, even after he feels better. The drug should be taken with a full glass of water and with food to prevent stomach upset. It should not be taken within 1 hour of bedtime to avoid esophageal irritation or ulceration. The medication should be protected from light and heat. Check the expiration date on the bottle of the drug because out-odate medication can cause nephrotoxicity. You should also encourage the client to use sun block and wear protective clothing during sun exposure. And instruct the client to report signs of superinfection (mouth ulcers, anal or genital discharge). Teach the client proper oral hygiene to prevent or alleviate mouth ulcers.
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