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Mitotane information for people that are required to take this medicine
Mitotane is a medication for treating cancer of the adrenal gland.
To monitor serious side effects it may have on a patient, mitotane is administered in a hospital setting. It is given with care to patients with liver disease, those who had undergone surgery, trauma or injury. It should be temporarily discontinued after a shock or severe trauma. Duration and dosage may be determined though regular behavioral, neurological and adrenal function assessments.
Mitotane may cause adrenal insufficiency so your doctor may also consider an adrenal steroid replacement to aid in your treatment.
Administration of this drug is given consideration when prescribing to nursing mothers, pregnant women and elderly. It is however not yet proven to be safe for children.
Tell your doctor before taking it if you are under medications like anticoagulants or medicines that cause sleepiness like muscle relaxers, sedatives, antidepressants or cold and allergy medicines. Avoid getting infections by staying away from people with cold or any contagious disease. Limit your activities that require alertness to avoid injury or trauma.
Mitotane tablets are swallowed whole without chewing, breaking or sucking. Crushed or broken tablets should be handled while wearing gloves and must be properly disposed.
As long as clinical benefits are observed, this treatment is continued. Some of the clinical benefits are maintenance of good clinical status and slowing of metastatic lesions growth. Reduction in tumor mass, pain and signs and symptoms of excessive production of steroid shows clinical effectiveness of this drug.
It has also side effects like all medicines have. Call the attention of your doctor if you have persistent and bothersome adverse reactions to this drug.
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