Why is Neoral prescribed?
Neoral is given after organ transplant surgery to help prevent rejection of organs (kidney, heart, or liver) by holding down the body's immune system. It is also used to avoid long-term rejection in people previously treated with other immunosuppressant drugs, such as Imuran. Neoral is a newer formulation of Neoral's active ingredient, cyclosporine. In addition to prevention of organ rejection, it is prescribed for certain severe cases of rheumatoid arthritis and psoriasis. Some doctors also prescribe Neoral to treat alopecia areata (localized areas of hair loss), aplastic anemia (shortage of red and white blood cells and platelets), Crohn's disease (chronic inflammation of the digestive tract), and nephropathy (kidney disease). Neoral is sometimes used in the treatment of severe skin disorders, including psoriasis and dermatomyositis (inflammation of the skin and muscles causing weakness and rash). The drug is also used in procedures involving bone marrow, the pancreas, and the lungs.
Neoral is always given with prednisone or a similar steroid. It is available in capsules and liquid, or as an injection.
Where can I order Neoral from? Can I buy
Neoral at Canadian Prices?
Yes, if you are from the U.S. then you can
buy Neoral at Canadian prices. Currently we will only
accept an order for Neoral from U.S. and Canadian residents.
Both U.S. and Canadian residents require a prescription to
purchase Neoral and when you order Neoral it will
be delivered with express shipping.
Most important fact about Neoral
If you take Neoral orally over a period of time, your doctor will monitor your blood levels of cyclosporine to make sure your body is receiving the correct amount of Neoral. The reason for this repeated testing is that the absorption of this drug in the body is erratic. Constant monitoring is necessary to prevent toxicity due to overdosing or to prevent possible organ rejection due to underdosing. It is important to note that Neoral may need to be taken by mouth for an indefinite period following surgery.
How should you take Neoral?
Take the Neoral capsule or oral liquid at the same time every day. You may take the medication either with a meal or between meals, but be consistent. To make Neoral oral liquid more palatable, you may mix it with room-temperature milk, chocolate milk, or orange juice. Try to use the same beverage as often as possible. Neoral oral solution may be mixed with room-temperature orange or apple juice. It does not taste good in milk. Use a container made of glass, not plastic. Never let the mixture stand; drink it as soon as you prepare it. To make sure you get your full dose, rinse the glass with a little more liquid and drink that too. You should maintain good dental hygiene and see your dentist frequently for cleaning to prevent tenderness, bleeding, and gum enlargement. After you use the dosage syringe to transfer the oral solution to a glass, dry the outside of the syringe with a clean towel and put it away. Do not rinse or wash it. If you do have to clean it, make sure it is thoroughly dry before you use it again. You may notice an odor when you open the capsule container; this is nothing to worry about and will soon dissipate. Neoral should start to work on rheumatoid arthritis in 4 to 8 weeks, and on psoriasis in 2 weeks. Psoriasis is usually controlled within 12 to 16 weeks; you should not take the drug for more than a year. --If you miss a dose...If fewer than 12 hours have passed, take it as soon as you remember. If it is almost time for the next dose, skip the one you missed and go back to your regular schedule. Do not take 2 doses at once. --Storage instructions...
Store both the capsules and the oral solution below 86 degrees F; do not store the liquid in the refrigerator. Keep the liquid from freezing. Neoral liquid, once opened, must be used within 2 months.
What side effects may occur with Neoral?
Side effects cannot be anticipated. If any appear or change in intensity, inform your doctor immediately. Only your doctor can determine if it is safe for you to continue taking Neoral. The principal side effects of Neoral are high blood pressure, hirsutism (unusual growth of hair), kidney damage, excessive growth of the gums, and tremor.
Other common side effects may include:
Abdominal discomfort, acne, breathing difficulty, convulsions, coughing, cramps, diarrhea, flu-like symptoms, flushing, headache, liver damage, lymph system tumor, muscle, bone, or joint pain, nasal inflammation, nausea, numbness or tingling, sinus inflammation, vomiting, wheezing
Less common side effects may include:
Abdominal distention, allergic reactions, anemia, appetite loss or increase, bleeding gums, blood disorders, brittle fingernails, confusion, conjunctivitis (pinkeye), dizziness, fever, fluid retention, frequent urination, hearing loss, hiccups, high blood sugar, indigestion, infection, insomnia, nervousness, peptic ulcer, rash and other skin disorders, ringing in the ears, stomach inflammation, vertigo
Rare side effects may include:
Anxiety, blood in the urine, breast development in males,
chest pain, constipation, depression, hair breaking, heart
attack, itching, joint pain, lymph disorders, mouth sores,
night sweats, sluggishness, stomach and upper intestinal bleeding,
swallowing difficulty, tingling, visual disturbance, weakness,
weight loss
Special information if you are pregnant or breastfeeding
The effects of Neoral in pregnancy have not been adequately studied. If you are pregnant or plan to become pregnant, inform your doctor immediately. Neoral should be used during pregnancy only if the benefit justifies the potential risk to the unborn child. Since Neoral appears in breast milk, it should not be used during breastfeeding. If you are a new mother, you may need to choose between taking Neoral and breastfeeding your baby.
Recommended dosage
ADULTS
Transplant Rejection
Your doctor will tailor your dosage of Neoral in accordance with your body's response. Expect a single dose of 15 milligrams per 2.2 pounds of body weight 4 to 12 hours before a transplant and 1 dose daily for 1 to 2 weeks after the operation. After that, the doctor may keep you on a daily dose of 5 to 10 milligrams per 2.2 pounds of body weight. The dosage of Neoral depends on the type of transplant and the other drugs you are taking. It is always taken twice a day. Psoriasis or Rheumatoid Arthritis The starting dosage is 2.5 milligrams of Neoral per 2.2 pounds of body weight divided into 2 doses per day. Your doctor may gradually increase the daily dose to a maximum of 4 milligrams per 2.2 pounds.
CHILDREN
Dosage is generally the same for children as for adults, though somewhat higher doses are sometimes needed. Both drugs have been used to prevent transplant rejection in small children. Neoral has not been tested for arthritis or psoriasis in children under 18.
Neoral
Although no specific information is available, an overdose of Neoral would be expected to cause liver and kidney problems. Any medication taken in excess can have serious consequences. If you suspect an overdose of Neoral, seek medical attention immediately.
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