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Raloxifene information for people that are required to take this medicine
Evista (Eli Lilly) is a selective estrogen receptor modulator (SERM) that reduces resorption of bone and decreases overall bone turnover with the generic name Raloxifene. It is primarily used for the prevention and treatment of osteoporosis in postmenopausal women. It is usually dispensed in 60 mg tablets. The recommended dosage is 60 mg/day, which may be administered any time of day without regard to meals.
Indications and Contraindications:
As women age, hormones regulating reproductive and bodily functions may diminish thus, minimal rate of hormone production can be observed during menopause. This makes the woman prone to several hormone-related diseases such as osteoporosis and breast problems. Fortunately, there are synthetic therapies that may replace what was once lost that includes Raloxifene which is known to control osteoporosis in women on their postmenopausal stage. It is also indicated in the reduction of the risk of breast cancer in women who are diagnosed with osteoporosis.
The usual recommended dosage of Raloxifene hydrochloride tablets is 60 mg daily, which can be given at any time of the day. Giving it at the same time each day is advised either with a full or empty stomach. However, if gastric irritation ensues, it is best to give the drug with meals. Supplemental calcium and vitamin D should be added to the diet if the daily intake is proven inadequate since 1500 mg/day of calcium is the recommended amount.
Contraindications
Raloxifene hydrochloride tablets cannot be given in women with active or past history of various types of embolism such as venous thromboembolism, deep vein thrombosis, pulmonary embolism, and retinal vein thrombosis. Likewise, the use of the drug is contraindicated in pregnancy, women who have plans of pregnancy, and in nursing mothers. Conditions such as heart disease, heart attack, and stroke contraindicate the use of the drug. The drug cannot be used with warfarin, ampicillin, cholestyramine, systemic estrogens, ampicillin, amoxicillin, antacids, corticosteroids, digoxin, and other highly protein-bound drugs as it may either potentiate or decrease the effects of Raloxifene.
One of the benefits of the drug has not been found to cause breast tenderness or enlargement. Take the drug exactly as prescribed to avoid overdose symptoms such as diarrhea, dizziness, flushing, loss of coordination, severe leg cramps, tremor, and vomiting.
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