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Selegiline information for people that are required to take this medicine
Selegiline Hyrdochloride is a Monoamine Oxidase Inhibitor (MAOI) used in the treatment of Cognitive Dysfunction Syndrome (CDS) and Cushing’s syndrome in dogs. It works by increasing the concentration of the neurotransmitter dopamine in the brain. Increased activity of MAO along the aging process leads to the decline of available dopamine in the brain. The enzyme MAO catalyzes neurotransmitters, which leads to the dog’s decreased mental functioning. Selegiline Hyrdochloride tablets are specially formulated to inhibit the process of such enzymes, thereby limiting the clinical signs brought about by CDS.
These tablets should not be given to those hypersensitive to Selegiline. It cannot be used along with narcotics, phenylpropanolamine, selective serotonin reuptake inhibitors, and other MAOIs such as amitraz and Mitaban. Make sure to notify your veterinarian about the vitamins, supplements, and medications your pet is taking before using Selegiline. Foods such as aged cheese cannot be given to dogs while undergoing Selegiline therapy, as it may lead to high blood pressure. Some reported adverse effects include anemia (check if gums are pale), diarrhea, disorientation, drooling, itching, lethargy, loss of appetite and hearing, restlessness, repetitive behaviors, shaking, and vomiting. It is best to stop therapy and consult the veterinarian immediately once any of these symptoms are seen.
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Administration of Selegiline Hyrdochloride:
• Selegiline Hyrdochloride is available in 2 mg, 5 mg, 10 mg, 15 mg, and 30 mg tablet forms..
• Give the medication early in the morning
• Store properly at room temperature, away from heat, moisture, and light.
• For the treatment of Cushing’s disease, this drug is given once a day for two months.
• For CDS, lower doses are given. Improvement may be seen in the first few days in some dogs, but a total effect will be noticed several weeks after start of treatment.
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