Trizivir is manufactured by GlaxoSmithKline Inc. This medicine is an antiviral combination used alone or with other medicines to manage human immunodeficiency virus (HIV) infection.
Why is Trizivir prescribed?
Trizivir combines three drugs used to fight HIV, the deadly virus that undermines the immune system, leaving the body ever more vulnerable to infection, and eventually leading to AIDS. The components of Trizivir are all members of the category of HIV drugs known as nucleoside analogs:
Abacavir (also called Ziagen)
Lamivudine (also called Epivir or 3TC)
Zidovudine (also called Retrovir, AZT, or ZDV)
Trizivir may be prescribed alone or in combination with other HIV drugs. It reduces the amount of HIV in the bloodstream, but does not completely cure the disease. You may still develop the rare infections and other complications that accompany HIV. Remember, too, that Trizivir does not reduce the risk of transmitting the virus to others.
Where can I order Trizivir from? Can I buy Trizivir
at Canadian Prices?
Yes, if you are from the U.S. then you can
buy Trizivir at Canadian prices. Currently we will only accept
an order for Trizivir from U.S. and Canadian residents. Both
U.S. and Canadian residents require a prescription to purchase
Trizivir and when you order Trizivir it will be delivered
with express shipping.
Most important fact about Trizivir
The abacavir (Ziagen) component of this medication which can cause a serious, possibly fatal allergic reaction. You should stop taking Trizivir and seek immediate medical attention if you develop any of the following symptoms: abdominal pain, body aches, cough, diarrhea, extreme fatigue, fever, general ill feeling, nausea, shortness of breath, skin rash, sore throat, vomiting. These symptoms usually appear during the first 6 weeks of therapy, but may occur any time during treatment. If they do occur, do not take another dose of Trizivir until you've seen your doctor. If you have to stop taking Trizivir because of this allergic reaction, you must never take Trizivir or Ziagen again. Once you've had such a reaction, taking either drug could lead to death within hours.
When your prescription for Trizivir is filled, the pharmacist will give you a "warning card" that lists the symptoms of an allergic reaction. Be sure to read it and to carry it with you.
How should you take Trizivir?
Trizivir is usually taken twice a day, with or without food. It is important to take the medication exactly as prescribed and not to miss any doses. Be sure to refill your prescription before your supply runs out. If HIV drugs are stopped for even a short time, the virus can increase rapidly and may become harder to treat. --If you miss a dose...Take it as soon as you remember. If it is almost time for your next dose, skip the one you missed and go back to your regular schedule. --Storage instructions...
Store Trizivir tablets at room temperature.
What Trizivir side effects may occur?
Trizivir Side effects cannot be anticipated. If any develop or change in intensity, inform your doctor as soon as possible. Only your doctor can determine if it is safe for you to continue taking Trizivir.
Trizivir Side effects may include:
Abdominal cramps, abdominal pain, allergic reaction, blisters
in the mouth or eyes, blood and lymph disorders, breast enlargement
in males, chills, cough, depression, diarrhea, dizziness, enlarged
spleen, fatigue, fever, hair loss, headache, heart problems,
high blood sugar, hives, ill feeling, indigestion, inflamed
blood vessels, insomnia and other sleep problems, joint pain,
liver problems, loss of appetite, mouth inflammation, muscle
pain or weakness, nasal symptoms, nausea, pain or tingling in
the hands or feet, pancreatitis, redistribution of body fat,
seizures, skin rash, vomiting, weakness, wheezing
Possible food and drug interactions when taking Trizivir
Do not combine Trizivir with Epivir, Combivir, Retrovir, or Ziagen, since these drugs contain ingredients in Trizivir. Also avoid Zerit while taking Trizivir.
In addition, if Trizivir is taken with certain other drugs, the effects of either may be increased, decreased, or altered. It is especially important to check with your doctor before combining Trizivir with the following:
Alcohol
Atovaquone (Mepron)
Doxorubicin (Adriamycin, Doxil, Rubex)
Drugs used for bone marrow suppression and cancer therapy
Fluconazole (Diflucan)
Ganciclovir (Cytovene)
Interferon-alpha (Intron, Roferon)
Methadone
Nelfinavir (Viracept)
Probenecid (Benemid)
Ribavirin (Virazole)
Ritonavir (Norvir, Kaletra)
Trimethoprim/sulfamethoxazole (Bactrim, Septra)
Valproic acid (Depakene)
Zalcitabine (Hivid)
Special Trizivir information if you are pregnant or breastfeeding
Trizivir has not been studied in pregnant women and should be used only if the benefit to the mother outweighs the potential risk to the developing baby.
Because the virus can be passed to a baby through breast milk, breastfeeding is not recommended for mothers with HIV.
Recommended Trizivirdosage
ADULTS
The recommended dose of Trizivir is 1 tablet twice daily with or without food.
CHILDREN
Trizivir is not intended for children and adolescents who weigh less than 90 pounds. Teenagers who weigh more than 90 pounds receive the adult dose.
Trizivir Overdosage
Any medication taken in excess can have serious consequences. If you suspect an overdose, seek medical attention immediately.
Symptoms of Trizivir overdose may include:
Confusion, dizziness, drowsiness, headache, lack of energy, nausea, vomiting
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